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However, the official development of intranasal PT-141 was canceled in 2008 due to concerns of adverse effects such as hypertension raised by phase-2 trials

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The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways

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High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health

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