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8.7 Individual difference factors modulating diet-depression associations 8.7.1 Age: shaping diet-induced depression progression Age affects the speed and severity of diet-induced depression by altering gut microbiota diversity, nutrient metabolism capacity, and neuroplasticityresulting in distinct risk profiles across life stages

Clinical trial percentages should not be interpreted as guarantees or typical individual outcomes

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Key results, as reported by the authors: Diet + placebo: 2.0% mean weight loss Diet + 0.25 mg: 4.5% mean weight loss, greater than diet and placebo Diet + 0.5 mg: 9.2% mean weight loss, greater than diet and placebo Diet + 1.0 mg: 10.6% mean weight loss, greater than diet and placebo The 0.5 mg dose was identified as the optimal balance between efficacy and tolerability

Nissley, 33, of Francisville, said shed never considered taking a weight loss drug before she learned it could help treat her condition

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