(1) J Ishida, M Saitoh, N Ebner, J Springer, et al (2020) Growth hormone secretagogues: history, mechanism of action, and clinical development JCSM Communications, Volume 3, Issue 1, January/June 2020, Pages 25-37
GLP-1s Arent the ProblemBut They Change the Environment Lets be clear: GLP-1 medications are not bad for your pelvic floor
What they found: Favorable safety profile , no serious adverse events at doses up to 100 g/kg Preliminary efficacy signals positive The program stopped before Phase 3 for unknown commercial reasons (the program passed through several sponsor rotations and no one ultimately carried it through) Why it matters: These are the only published clinical data in humans that we have
Adults over 50 and vegetarians are more likely to suffer from a B-12 deficiency, so B-12 injections may be ideal for older individuals trying to manage their health
Traceable compound numbers
On the other hand, the p75 NTR receptor has been reported to either induce or prevent apoptosis upon oxidative insult in both in vivo and in vitro models