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Genetic analysis of Caenorhabditis elegans glp-1 mutants suggests receptor interaction or competition

GLP-1 stimulates insulin secretion, inhibits glucagon release, and, perhaps most notably, suppresses appetite and reduces food intake [14]

GLP-1 RAs promote diuresis and natriuresis by inhibiting sodium reabsorption in the renal proximal tubule through the Na + /H + exchanger isoform 3 (NHE3) [77]

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