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When it is produced by our bodies, which happens in the kidneys, brain and liver, its not metabolised by the gut microbiota and isnt converted to TMAO
L-carnitine 97%
Both peptides remain research tools, and any discussion of dosing, administration strategies, or effects must be understood as mechanistic hypothesis rather than established clinical practice
The critical insight is that leucine by itself depleted muscle isoleucine by 55% and valine by 42% during recovery, creating substrate limitations for protein synthesis
doi: 10.21037/jtd-cus-2020-012 35