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This reabsorption may increase the risk of side effects such as breast tenderness, weight gain, and even thromboembolic events

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and Swedish scientists, found no increased risk

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Another randomized controlled trial showed that soybean isoflavone therapy (80 mg/day, P.O for 24 weeks) significantly increased the protein and mRNA levels of Nrf2 and the concentrations of SOD as well as diminished serum levels of inflammatory factors and MAD in patients with myocardial ischemia [139]