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Here's what the data showed: Weight Loss by Dose (48 Weeks) Why this matters: The FDA-approved semaglutide (Wegovy) produced around 1517% weight loss in its pivotal trials

doi: 10.1016/j.cub.2009.03.017

For timeline-specific guides, see tirzepatide weight loss timeline , semaglutide results week by week , and when you start losing weight on semaglutide

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The drugs side effects are expected to be similar when used off-label for weight loss

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