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The most commonly reported adverse effects of tirzepatide are gastrointestinal in nature, occurring in a substantial proportion of patients during initial treatment and dose escalation
They will: Review your medical history with you
An earlier Phase 3 trial in people with obesity and knee osteoarthritis, TRIUMPH-4, found an average weight loss of 28.7% at the same dose, alongside a reduction in joint pain
This lowers the sugar level in your blood, which is especially important for people with diabetes who often have high blood sugar levels
If they persist or worsen, contact your provider
