Ceriello A, Esposito K, Testa R, Bonfigli AR, Marra M, Giugliano D: The possible protective role of glucagon-like peptide 1 on endothelium during the meal and evidence for an endothelial resistance to glucagon-like peptide 1 in diabetes
DOI: 10.1172/JCI194751.
Summary: Tiredness on GLP-1 medications typically results from reduced caloric intake, nutritional imbalances, dehydration, and metabolic adaptation as your body adjusts to treatment
Conversely, a study by Gasbjerg et al
Although these medications can silence food noise, reduce externally cued eating, and show early promise in addiction-related outcomes, current evidence does not show that they reliably resolve emotional eating or uniformly improve mood across all users
This review has significant implications for the management of T2D, making it a compelling read for healthcare professionals, researchers, and clinicians