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Hydroxocobalamin is an injectable form of vitamin B12 used to treat and prevent vitamin B12 deficiency

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Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss

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A prospective randomized controlled clinical trial was performed, enrolling 70 consecutive patients who underwent TACE

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