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Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated substantial weight loss in participants with obesity, though these findings were generated under tightly controlled conditions with rigorous medical supervision
These subclusters exhibited the highest expression of ARX and DNMT1 , suggesting that these subpopulations represent the most mature cell subclusters (Figure 3E
10.1002/1097-0215(20001101)88:3 3.0.CO;2-F Int
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Activation of NRF2 is reported to coincide with the repression of enzymes involved in adipogenesis (Fig
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