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Duodenum: Free fatty acid receptor (FFAR) 1 and CaSR, expressed on I cells, mediate CCK secretion in response to fatty acids and amino acids (98, 99)

Semaglutide STEP 1 Trial New England Journal of Medicine (2021) Semaglutide 2.4 mg 14.9% 68 2.4% STEP 2 2 9.6% STEP 4 20 17.4% SELECT Trial (2023) Semaglutide (MACE) 20% Semaglutide HbA1c 2 1.52.0% 36 mmHg LDL-Cholesterol Semaglutide

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These gastrointestinal issues could be fatal without urgent medical attention

Other medications that cause drowsiness, such as beta-blockers to control blood pressure, are often used by people with type 2 diabetes