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Synthesis of MMP-2 and MMP-3 is vitally risen in synovium at the periphery of hyaline cartilage in inflammatory joints [113,114,115]

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Published literature includes over 100 studies examining its effects in various in-vitro and animal model systems, with research groups investigating gastrointestinal cytoprotection, tendon and ligament tissue models, and neurological signaling pathways

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Neither provided information about the randomisation process, complete outcome data and full reporting of results