Depending on the medication and the patient population, research and approvals have supported benefits in areas like: Cardiovascular risk reduction in adults with established cardiovascular disease and overweight or obesity (for specific products) Kidney protection in people with type 2 diabetes and chronic kidney disease (semaglutide showed benefit in a large kidney outcomes trial) Obstructive sleep apnea in adults with obesity (tirzepatide has an FDA-approved indication for moderate to severe OSA in this population) Fatty liver disease and MASH (semaglutide has shown promising results in phase 3 research) Addiction to opioids and alcohol This is why these medications are now part of bigger medical conversations: heart, kidney, liver, sleep health and substance abuse
A drop should appear at the needle tip that confirms the pen is delivering medication
Her use of these GLP-1 RA drugs caused her to experience severe gastrointestinal distress
This makes it convenient for those who prefer not to use injections
As mentioned earlier, the aim when on Mounjaro is to have your maintenance strength be as low as possible while still being effective
For example, the largest STEP trial published to date reported that GI issues affected 74.2% of volunteers taking semaglutide, as opposed to 47.9% taking placebo
