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January 26, 2024

Lippincott Williams & Wilkins

GH itself supports lipolysis (fat burning) and IGF-1 production, which downstream supports protein synthesis

Ana Sierra: go

Importantly, these changes might be linked to an increase in ketogenesis and favorable changes in gut microbiota, which were even observed after an isocaloric LCD [42]

We chose SGLT-2 inhibitors as the secondary comparator because they are also used at a disease stage similar to GLP-1 receptor agonists and have not been associated with the outcome.16 For both cohorts, we defined cohort entry as the date of the first prescription for either a GLP-1 receptor agonist or the comparator drug during the study period