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Highly reactive oxygen-containing molecules such as superoxide (O), hydrogen peroxide (HO), hydroxyl radicals (OH) and peroxyl radicals (OOH) that are by-products of cellular metabolism that at low levels function in cell signalling and immune defence, but when produced in excess result in oxidative stress, damaging cellular structures such as DNA, proteins and lipids

10.1016/j.freeradbiomed.2009.12.022 33 ColuzziE.LeoneS.SguraA

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Carnitine regulates myocardial metabolism by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha) in alcoholic cardiomyopathy

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Danshen improves survival of patients with breast cancer and Dihydroisotanshinone I induces ferroptosis and apoptosis of breast cancer cells