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Endothelial nuclear factor-B and the initiation of the atherosclerotic lesion

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Philip Morris International has not submitted the adequate scientific evidence required by US law demonstrating that marketing IQOS in the USA would be appropriate for the protection of the public health, or demonstrating that IQOS is significantly less harmful to users than other tobacco products, that its labelling would not mislead consumers or that its marketingwith or without modified risk claimswould benefit the health of the population as a whole