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Slow recovery after physical exercise or long days

Similar to proteasome inhibitors (e.g., MG132 and bortezomib), CuET induces accumulation of ubiquitylated proteins and rapid deubiquitylation of histone H2A in MCF-7 cells (Skrott et al., 2017)

doi:10.1016/j.jns.2003.11.005 Dhanoa TS, Housner JA

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In the same study, glutamic pyruvate transaminase was five-fold higher in periportal hepatocytes versus centrilobular hepatocytes but increased in both areas of the lobule during a three-day fast