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Moreover, the apoptotic machinery itself regulates mitochondrial clearance during terminal erythropoiesis, e.g., Nix protein mediates autophagy-dependent mitochondrial elimination in reticulocytes [116]

Natural sources include red meat, fish, poultry, and dairy

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Plants normally have numerous mechanisms that hamper alkaline toxicity, such as inhibition of Na uptake, and prevention of its accumulation by binding with exudates of roots, intracellular sequestration by phytochelatins and strong ligands, such as cysteine-rich compounds 8

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The risk of contamination rises exponentially, and the reconstituted solution should ideally be discarded within 24 hours