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Nature 447 , 10811086 (2007)

As described by Vardhini et al

Tranexamic Acid: A clinically proven brightening agent that inhibits melanin production in epidermal cells prevents the appearance of pigmentation, dark spots, and post-inflammatory marks without photosensitivity or irritation

Downstream signaling involves PI3K/AKT, MAPK/ERK, and PLC- pathways, which are well-characterized drivers of synaptogenesis, dendritic spine maturation, and neuronal survival