5 Future directions The potential of GLP-1RAs as dual-action therapies, targeting both metabolic dysfunction and immune dysregulation, makes them particularly compelling candidates for early PsA, where intervention may alter disease trajectory
Nausea and Vomiting: The study identified associations linking variation in both the GLP1R and GIPR genes to GLP-1 medication-related nausea or vomiting
Early evidence indicates that people taking GLP-1 medications for diabetes or weight loss reported reduced interest in alcohol and other addictive substances
Care that includes integrated nutrition and physical activity support, as well as associated lifestyle modifications, can help ensure patients maintain improved health for a longer duration
It is important that people who take prescription GLP-1s consider all of the risks, known and unknown
Gastrointestinal side effects Both phentermine and tirzepatide affect the gastrointestinal system, though through different mechanisms