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94 Naive embryonic stem cells, such as those primed by NAD, also consume glutamine as an important nutrient and produce a-ketoglutarate for H3K27me3 demethylation, thereby maintaining the hypomethylated state of embryonic stem cells

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(2016) were the first to demonstrate that transplanting fecal matter from PD patients into mice genetically engineered to overexpress alpha-synuclein significantly worsened their motor symptoms compared to mice receiving transplants from healthy human donors