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In an ad-libitum meal experiment with varying fat content, patients with MC-4R mutations consumed 95% more of the high-fat meal compared to lean controls, and 65% more compared to obese controls

Tirzepatide is given through weekly injections, usually administered in the abdomen, thigh, or upper arm

Ozempic and Rybelsus are currently approved to lower blood sugar (glucose) levels in adults with type 2 diabetes, when used in combination with diet and exercise

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